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March 5, 2026Annals of Internal Medicine2 citations

Efficacy, Comparative Effectiveness, and Harm of Respiratory Syncytial Virus Vaccines in Adults Who Are Not Pregnant or Immunocompromised: A Rapid Review for the American College of Physicians

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IMIsabel T.K. MoserADAndreea I. DobrescuISIsolde Sommer

Key Points

  • This review aims to evaluate the efficacy and comparative effectiveness of respiratory syncytial virus vaccines in adults who are not pregnant or immunocompromised.
  • Conducted a rapid review to gather existing data on vaccine efficacy
  • Focused on adult populations who are not pregnant or immunocompromised
  • Reviewed comparative effectiveness against other respiratory viruses
  • Identified varying levels of efficacy among different vaccine candidates
  • Highlighted potential safety concerns for certain vaccine options
  • Found evidence suggesting improved outcomes in vaccinated adults

Abstract

American College of Physicians. (PROSPERO: CRD420251145237).

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Cite This Study

Moser et al. (2026) studied this question.

synapsesocial.com/papers/69a91cbed6127c7a504bfa04https://doi.org/10.7326/annals-25-05536
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