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March 7, 2026DENTAL JOURNAL OF INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCES0 citationsOpen Access

Exfoliative Cheilitis- From Challenges to Cure: A Case Report

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SSShubha SharmaCSChristopher Vinay ShindeHHH Handa

Key Points

  • The paper aims to report on the management of exfoliative cheilitis using specific treatment protocols.
  • Described a case of a 21-year-old female with exfoliative cheilitis.
  • Administered intralesional corticosteroid injections weekly for one month.
  • Provided psychological counselling alongside topical tacrolimus and oral supplements.
  • Effective reduction in symptoms of dryness, itching, and cracking of lips.
  • Improvement in condition without adverse effects observed.
  • Highlighting the importance of combined therapeutic approaches in treatment.

Abstract

Cheilitis refers to the inflammation of the vermilion border of the lips. Exfoliative cheilitis manifests on both upper and lower lips characterized by shedding of keratinized surface layers, leading to excessive peeling of thickened scales, redness and swelling. It is commonly associated with nutritional deficiencies, psychiatric conditions like depression, anxiety, self-injurious behaviour and is often exacerbated by habits such as lip licking and biting. We report a case of a twenty one years old female patient with the chief complaint of dry, itchy and cracked lower and upper lips. She was treated previously by a dermatologist for her lips without any signs of improvement. Intralesional corticosteroid injections of triamcinolone acetonide 40mg/ml were given once a week for a month with effective psychological counselling. Topical tacrolimus 0.1% ointment with oral multivitamins and iron supplements was prescribed. The absence of specific treatment renders exfoliative cheilitis a chronic condition significantly impacting an individual's quality of life. This paper aims to present a case where exfoliative cheilitis was effectively managed using topical tacrolimus and intralesional corticosteroids, resulting in alleviated symptoms without encountering adverse effects.

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Cite This Study

Sharma et al. (2026) studied this question.

synapsesocial.com/papers/69abc1645af8044f7a4ea0fahttps://doi.org/10.25259/djigims_44_2025
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Treatment of Granulomatous Cheilitis With Infliximab2005 · 63 citations
  2. 2Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03%2020 · 10 citations
  3. 3RETRACTED ARTICLE: Topical Calendula officinalis L. successfully treated exfoliative cheilitis: a case report2009 · 33 citations
  4. 4Exfoliative Cheilitis a male patient – a case report2015 · 7 citations
  5. 5Predisposition of hypersensitivity in patients with exfoliative cheilitis2021 · 12 citations