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March 13, 20260 citationsOpen Access

Mediating Role of Depression between Emotion Regulation Strategies and Suicide Proneness among Male Patients with Substance Use Disorder

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HHHasnain HyderS(Salman Shahzad (Ph.D)ILIbarat Ali Laghari

Key Points

  • To investigate how depression mediates the relationship between emotion regulation strategies and suicide proneness in males with substance use disorder.
  • Cross-sectional quantitative design
  • 180 male participants recruited from rehabilitation centers
  • Instruments used: Emotion Regulation Questionnaire, Siddiqui Shah Depression Scale, Life Attitude Schedule Short Form
  • Mediation analyses conducted using PROCESS Macro (Model 4)
  • Correlation and descriptive statistics were performed
  • Affective suppression positively correlated with both depression and suicide proneness.
  • No correlation was found between cognitive reappraisal and depression or suicide proneness.
  • Mediation analysis indicated that depression mediates the relationship between affective suppression and suicide proneness.
  • Cognitive reappraisal was also mediated by depression in relation to suicide proneness.

Abstract

This paper was set out to explore the mediating factor of depression in the interrelationship between emotional regulation (i.e. affective suppression and cognitive reappraisal) and suicide-proneness among males with Substance Use Disorder (SUD). It used a cross-sectional quantitative design and recruited 180 male participants who were recruited through a purposive sampling technique in Karachi in rehabilitation centres that are located in urban areas. The tools that were used to obtain the data include the Emotion Regulation Questionnaire (ERQ), the Siddiqui Shah Depression Scale (SSDS), and the Life Attitude Schedule Short Form (LAS-SF), which are standardised tools. It was analysed with the help of mediation analyses with the help of the PROCESS Macro (Model 4), Pearson correlations, and descriptive statistics. Findings indicated that affective suppression positively correlated with depression and suicide proneness, but no positive correlation was found between cognitive reappraisal and depression and suicide proneness. Mediation analysis showed that depression mediated the correlation between both the affective suppression and suicide proneness, and the cognitive reappraisal and suicide proneness. The research concludes that depression is a very important psychological process connecting emotion regulation and suicidal risk. These results support the importance of culturally specific cognitive-behavioural and emotion-focused interventions in enhancing the process o

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Cite This Study

Hyder et al. (2026) studied this question.

synapsesocial.com/papers/69b3ac4d02a1e69014ccddfahttps://doi.org/10.5281/zenodo.18957945
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mediating Role of Depression in the Relationship between Substance Use and Suicide Proneness among Adolescents in Underserved Communities in Pakistan2025
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  3. 3The association between emotion dysregulation and suicidal ideation in males with bipolar disorder and major depressive disorder in remission; a comparative study2026
  4. 4An examination of the mediating role of maladaptive emotion regulation strategies in the complex relationship between interpersonal needs and suicidal behavior2024 · 20 citations
  5. 5The Modeling Effect of Depression and Behavioral Disorders and Problematic Smartphone Use on the Possibility of Suicide Attempt among Male Adolescents based on the Mediating Role of Coping Strategies2025