Chordoma is a rare, slow-growing yet locally aggressive malignant tumor originating from embryonic remnant notochord tissue. Jugular foramen chordomas pose significant treatment challenges due to their deep location and critical surrounding structures. Clinical symptoms primarily result from tumor compression and erosion of adjacent nerves and blood vessels. This case presents a 59-year-old male patient with jugular foramen chordoma. The diagnosis was confirmed through a combination of imaging studies, 3D Slicer multimodal image fusion reconstruction, pathology, and laboratory tests. The main manifestations were hearing loss in the left ear for 10 years, hoarseness for 1 year, and left-sided facial paralysis for 3 months. Imaging revealed a tumor in the jugular foramen region. The tumor was resected through a translabyrinthine-infralabyrinthine approach, and the patient recovered well postoperatively. This paper aims to explore the diagnosis, treatment, and prognosis of chordoma of the jugular foramen through this case, emphasizing the importance of multidisciplinary collaboration in comprehensive management and providing a reference for clinical practice.
Zhang et al. (2026) studied this question.