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March 18, 2026Lishizhen medicine and materia medica research0 citations

Research progress on the treatment of diabetic osteoporosis via regulating Treg/Th17 cell balance in TCM

KSKexin SHIZWZhimin WangYCYiran CHEN

Key Points

  • The aim is to understand the role of Treg/Th17 cell balance in diabetic osteoporosis and explore the therapeutic potential of traditional Chinese medicine (TCM).
  • Systematic review of literature focusing on Treg/Th17 imbalances in diabetic osteoporosis.
  • Analysis of traditional Chinese medicine interventions affecting immune cell regulation.
  • Investigation of the mechanisms through which TCM influences Treg/Th17 balance.
  • Identified a significant link between immune imbalance and diabetic osteoporosis.
  • Highlighted Treg/Th17 cell balance as a critical factor in disease pathology.
  • Demonstrated potential of TCM in restoring Treg/Th17 balance, though further research is needed.

Abstract

糖尿病骨质疏松症(DOP)是由血糖异常高水平引发的一种骨性疾病,该病机制尚未完全阐明。随着 DOP 发病机制与免疫失衡之间的联系被不断揭示,尤其是调节性 T 细胞(Treg)和辅助性 T 细胞17(Th17)作为免疫调节的关键成分,调控 Treg/Th17平衡成为当前治疗糖尿病骨质疏松症的新方向。中医药以多层次,多角度进行诊疗,已展示其显著疗效,但目前探索中医药调节 Treg/Th17平衡治疗糖尿病骨质疏松症的机制研究仍未充分。文章对 Treg/Th17失衡在 DOP 中的发病机制,以及中医药调节 Treg/Th17平衡治疗糖尿病骨质疏松症的研究进行系统综述,以期为 DOP 的防治提供新的切入点。

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Cite This Study

SHI et al. (2026) studied this question.

synapsesocial.com/papers/69ba42cf4e9516ffd37a36c0https://doi.org/10.70976/j.1008-0805.szgygy-2026-0318
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