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March 25, 2026Veterinary Sciences0 citationsOpen Access

A Practical Diagnostic Approach to Non-Drowning Asphyxia in Animals: Forensic Pathology and Biomarkers

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VRVittoria RomanoDBDavide De BiaseVRV. Russo

Key Points

  • The aim is to explore the diagnostic difficulties and necessary criteria for identifying non-drowning asphyxia in veterinary cases.
  • Review of different mechanisms of asphyxia
  • Analysis of diagnostic challenges in veterinary forensic pathology
  • Discussion of necessary ancillary tests and histological findings
  • Identified various categories of asphyxia including strangulation and suffocation
  • Emphasized the subtle signs of fatal asphyxia leading to diagnostic difficulties
  • Outlined the importance of comprehensive information including crime scene and medical history for accurate diagnosis

Abstract

The term asphyxia refers to a disruption in brain function due to rapid and persistent cerebral hypoxia or anoxia as a consequence of accidental or non-accidental injury. Considering the different mechanisms that may determine asphyxiation, such injuries can be referred to different categories: strangulation (death by hanging, ligature or manual strangulation), suffocation (smothering, choking, confined spaces and vitiated atmosphere), mechanical asphyxia (positional and traumatic asphyxia) and drowning (submersion or immersion in liquid). In both human and veterinary forensic practice, fatal asphyxia is considered among the most diagnostically challenging categories of sudden death, as it often produces only subtle and non-pathognomonic macroscopic signs, which can be easily covered by post-mortem alterations. Therefore, a wide range of information is often needed for the diagnosis of asphyxiation, including medical history, crime scene analysis, testimonies and physical evidence, along with the macroscopic and histological findings. The following review addresses the main lesions, ancillary tests and diagnostic issues associated with non-drowning asphyxia in veterinary forensic pathology.

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Cite This Study

Romano et al. (2026) studied this question.

synapsesocial.com/papers/69c37be2b34aaaeb1a67ec53https://doi.org/10.3390/vetsci13030296
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