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March 26, 2026Organic & Biomolecular Chemistry0 citations

Discovery of artemargyins A-E: rare 9'-nor-dibenzylbutane lignans and a lignan-coumarin hybrid with antihepatic fibrosis activities from Artemisia argyi var. gracilis

YWYing Nian WuZMZe MaYHYongxiang Huang

Key Points

  • This research aims to isolate and characterize novel lignans from Artemisia argyi var. gracilis and evaluate their antihepatic fibrosis properties.
  • Isolated artemargyins A-E and known compounds from plant material
  • Utilized comprehensive spectroscopic techniques for structural elucidation
  • Employed theoretical ECD calculations for configuration determination
  • Five new lignans (artemargyins A-E) were successfully isolated
  • Presence of antihepatic fibrosis activities was confirmed
  • Structures were elucidated using advanced spectroscopic methods

Abstract

Artemargyins A-E (1-5) along with three known compounds (6-8) were isolated from Artemisia argyi var. gracilis. Their structures and absolute configurations were elucidated by comprehensive spectroscopic data, theoretical ECD calculations...

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Cite This Study

Wu et al. (2025) studied this question.

synapsesocial.com/papers/69c4cc85fdc3bde448917da8https://doi.org/10.1039/d6ob00214e
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