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March 26, 2026Critical Care Medicine0 citations

Chronic Vs Acute Hyperglycemia Effects On Blood Transfusion During Cardiac Surgery

131: Chronic vs Acute Hyperglycemia: Distinct Drivers of Blood Transfusion in Cardiac Surgery

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Authors

CDCatalina DussanMCMaria CastanoALAmmar M. Lakda

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Overview

A quality improvement initiative evaluates transfusion needs linked to diabetes and intraoperative glucose in cardiac surgery.

Key Points

  • This initiative aimed to assess the influence of diabetes and intraoperative glucose on blood transfusion during cardiac surgery. It seeks to optimize resource use and risk stratification.
  • Retrospective analysis of 24,005 adult patients undergoing cardiac surgery from January 2018 to June 2024.
  • Exclusions included repeat surgeries and transplants.
  • Primary outcome measured was the total blood product units transfused intraoperatively and postoperatively.
  • Multivariable negative binomial regression was used to adjust for clinical and surgical variables.
  • Diabetes status was defined by preoperative diagnosis and intraoperative glucose levels analyzed as a continuous covariate.
  • Diabetes mellitus (DM) was present in 6,071 patients (25%).
  • Median transfusion volume was 2 units for patients with DM and 1 unit for those without.
  • After adjustment, DM was associated with fewer transfusions (GMR 0.94; p<0.01).
  • Each 10 mg/dL rise in intraoperative glucose correlated with increased transfusion needs (GMR 1.02; p<0.01).
  • Chronic hyperglycemia is linked to reduced transfusion needs, while acute hyperglycemia increases them.
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Cite This Study

Dussan et al. (2026) studied this question.

synapsesocial.com/papers/69c4ccaffdc3bde4489181efhttps://doi.org/10.1097/01.ccm.0001182520.40438.a9
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Dysglycaemia and the interaction of chronic and acute glycaemia with mortality post cardiac surgery2025
  2. 27481 Beyond the Operation Room: A Retrospective Study on Diabetes and Post-Operative Hyperglycemia Outcomes2024
  3. 3Perioperative Glycemic Control and Outcomes in Cardiac Surgery: A Retrospective Cohort Study.2026
  4. 4Blood glucose management in the patient undergoing cardiac surgery: A review2014 · 39 citations
  5. 5Risk factors and impact of postoperative hyperglycemia in nondiabetic patients after cardiac surgery2019 · 40 citations