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March 28, 20260 citations

大黄䗪虫丸对胃癌并2型糖尿病患者化疗耐受性的影响

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耘伏耘慷 伏

Key Points

  • This research aims to evaluate the effect of Da Huang Chong Wan combined with XELOX chemotherapy on tolerance and quality of life in patients with gastric cancer and type 2 diabetes.
  • 124 patients with gastric cancer and type 2 diabetes were randomly assigned to either control or observation groups.
  • Both groups received XELOX chemotherapy, with the observation group receiving additional Da Huang Chong Wan.
  • Rates of adverse reactions, chemotherapy withdrawal, and quality of life scores were monitored.
  • Fasting blood glucose and postprandial blood glucose levels were also measured.
  • The adverse reaction and chemotherapy withdrawal rates in the observation group were lower than those in the control group (P<0.05).
  • Quality of life scores significantly improved in both groups post-treatment, with the observation group scoring higher than the control group (P<0.05).
  • Fasting blood glucose and postprandial blood glucose levels were elevated in the control group after treatment, while they decreased in the observation group (P<0.05).

Abstract

【摘要】 目的: 探讨大黄䗪虫丸联合XELOX方案对气滞血瘀型胃癌合并2型糖尿病(type 2 diabetes mellitus,T2DM)患者化疗耐受性及生存质量的影响。 方法: 随机将124例胃癌合并T2DM患者分成对照组和观察组各62例,分别给予XELOX化疗和XELOX化疗联合大黄䗪虫丸治疗。观察两组不良反应发生率、退出化疗百分率、欧洲癌症研究与治疗组织生命质量测定量表(EORTC QLQ-C30)评分、空腹血糖(FPG)和餐后2 h血糖(2 h PPG)水平。 结果: 观察组不良反应发生率和化疗退出率均低于对照组(PPPPPP 结论: 在XELOX方案基础上联合大黄䗪虫丸用于气滞血瘀型胃癌合并T2DM患者,可有效提高化疗耐受性,改善生存质量,并对血糖控制产生积极影响。

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Cite This Study

耘慷 伏 (2025) studied this question.

synapsesocial.com/papers/69c7724e8bbfbc51511e2bbahttps://doi.org/10.70976/j.1672-7851.dw250043
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