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March 30, 2026New Microbes and New InfectionsOpen Access

Worldwide Prevalence of Chlamydia trachomatis in Infertile Women: A Systematic Review and Meta-analysis

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Authors

VGVida GhasemiMRMosayeb RostamianMTMahboubeh Taebi

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Overview

Systematic review assesses high prevalence of Chlamydia trachomatis in infertile women, indicating need for routine screening.

Key Points

  • To estimate the global prevalence of Chlamydia trachomatis among infertile women through systematic review and meta-analysis.
  • Conducted systematic search in Medline, Web of Science, and Scopus databases.
  • Included studies from 2010 to July 2025 based on specified keywords.
  • Estimated prevalence using random-effects model meta-analyses and 95% confidence intervals.
  • Performed subgroup analyses based on detection method and sample type.
  • Conducted meta-regression to evaluate prevalence relation with age and year of publication.
  • Overall pooled prevalence of Chlamydia trachomatis among infertile women was 24.1% (95% CI: 17.1–33.0).
  • Blood samples showed the highest prevalence at 45.7% (95% CI: 34.7–57.2).
  • ELISA detection method reported the highest prevalence of 26.9% (95% CI: 14.4–44.5).
  • Real-time PCR in endocervical samples had a prevalence of 20.5% (95% CI: 11.8–33.3), indicating high sensitivity.
  • Study highlights the importance of routine CT screening in improving infertility assessments.

Cite This Study

Ghasemi et al. (2026) studied this question.

synapsesocial.com/papers/69ca12d4883daed6ee0950ebhttps://doi.org/10.1016/j.nmni.2026.101745
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Also Consider

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