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April 1, 2026Urology Case ReportsOpen Access

Steering Clear of Incorrect Laboratory Reference Ranges in Leydig Cell Testicular Tumor–Induced Peripheral Precocious Puberty: A case report

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Authors

NSNoor SawalhaHHHeba HrizatFTFatima Thawabteh

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Overview

A case report reveals the diagnostic challenges of laboratory reference ranges in a child with precocious puberty, suggesting the need for a multidisciplinary approach.

Key Points

  • To highlight the complexities in diagnosing Leydig cell tumors in pediatric patients presenting with precocious puberty.
  • Case report of an 8-year-old boy with early pubertal signs
  • Assessment included biochemical tests and ultrasound imaging
  • Histopathological confirmation following unilateral orchiectomy
  • Normal testosterone levels observed despite signs of precocious puberty
  • Advanced bone age noted in the patient
  • Histopathology confirmed the diagnosis of Leydig cell tumor
  • Ultrasound revealed right intratesticular lesion indicating the tumor

Cite This Study

Sawalha et al. (2026) studied this question.

synapsesocial.com/papers/69ccb63f16edfba7beb87eaehttps://doi.org/10.1016/j.eucr.2026.103427
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