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April 1, 2026Open Access

1,3-Dichlorobenzene – Evaluation of a biological guidance value (BLW)

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Authors

AKAndrea KaifieWWWobbeke WeistenhöferTKThomas Kraus

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Overview

Evaluation finds a biological guidance value for 1,3-dichlorobenzene, suggesting occupational exposure limits.

Key Points

  • This evaluation aims to establish a biological guidance value (BLW) for 1,3-dichlorobenzene based on relevant studies.
  • Identified relevant publications through a literature search.
  • Derived BLW from an experimental study correlating air and blood concentrations of 1,3-dichlorobenzene.
  • Extrapolated data for an 8-hour exposure using resting volunteer data.
  • Applied a MAK value of 2 ml/m3 to determine expected urinary metabolite levels.
  • A BLW of 40 mg of 3,5-dichlorocatechol per gram of creatinine was established.
  • The correlation between air concentration and blood levels showed strong consistency.
  • Sampling for metabolite analysis occurs at the end of shifts after repeated exposure.

Cite This Study

Kaifie et al. (2026) studied this question.

synapsesocial.com/papers/69ccb7b016edfba7beb89bbfhttps://doi.org/10.34865/bb54173e11_1or
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