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April 1, 2026International Heart Journal0 citationsOpen Access

Incidence And Outcomes Of Acute Aortic Dissection In Rural Japan

Population-Based Incidence and Outcomes of Acute Aortic Dissection in Rural Areas of Japan

Population

Patients diagnosed with acute aortic dissection in the rural Rumoi medical area of Japan, mean age 75.7…

Design

Cohort

Follow-up

30-day

Key result

Acute aortic dissection had an age-adjusted incidence of 17.3 per 100,000 inhabitants per year in rural Japan, with a 6.7% 30-day mortality rate among patients alive on hospital arrival.

Authors

FTFumihiko TakahashiYSYasuaki SaijoHKHiroyuki Kamiya

Discussion

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Overview

Prompt diagnosis and early tertiary transfer may reduce rural AAD mortality; extends urban data to non-urban Japanese cohorts.

Key Points

  • This research aims to analyze the incidence and outcomes of acute aortic dissection in rural Japan.
  • Conducted a retrospective review of AAD patients in the Rumoi medical area from 2014 to 2023
  • Identified 67 cases of AAD and collected data on demographics and outcomes
  • Analyzed age-adjusted incidence and mortality rates
  • Age-adjusted incidence rate of AAD was 17.3 per 100,000 inhabitants per year
  • 30-day mortality among patients alive on arrival was lower than previous reports
  • All transferred patients with type A AAD underwent emergency surgery

Study Design

Type

Observational (n=67)

Multicenter

No

Structured PICO

P
Population
Patients diagnosed with acute aortic dissection (AAD) in the rural Rumoi medical area of Japan, mean age 75.7 years, 59.7% male.
O
Outcome
Age-adjusted incidence and mortality rates of AAD per 100,000 inhabitants per yearhard clinical

Prompt diagnosis and early transfer to tertiary referral hospitals can reduce the 30-day mortality rate of acute aortic dissection even in rural settings.

Limitations

  • Single-center study with a relatively small sample size compared with previous reports.
  • Some patients with AAD might have been diagnosed or treated at facilities outside the medical area.
  • Autopsy imaging was not performed for all patients who were dead on arrival, possibly leading to underestimation of the true incidence and mortality rates.
  • Single-center study with a relatively small sample size
  • Some patients might have been diagnosed or treated at facilities outside the medical area
  • Autopsy imaging was not performed for all patients who were dead on arrival, possibly leading to underestimation of the true incidence and mortality rates
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Cite This Study

Takahashi et al. (2026) conducted an observational in Acute aortic dissection (n=67). Acute aortic dissection had an age-adjusted incidence of 17.3 per 100,000 inhabitants per year in rural Japan, with a 6.7% 30-day mortality rate among patients alive on hospital arrival.

synapsesocial.com/papers/69cd79bb5652765b073a692ehttps://doi.org/10.1536/ihj.25-619
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epidemiology of Acute Aortic Dissection in a General Population of 1.4 Million People in Japan　― Shiga Stroke and Heart Attack Registry ―2023 · 13 citations
  2. 2Comparative Long-Term Prognosis of Acute Myocardial Infarction and Acute Aortic Dissection in a Population-Based Registry2026
  3. 3Dissecting the epidemiology of aortic dissection2021 · 14 citations
  4. 4Newly Diagnosed Acute Aortic Dissection2005 · 28 citations
  5. 5Acute aortic dissection: Clinical characteristics and outcomes2022