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April 13, 20260 citationsOpen Access

Effects Of Non-Steroidal Anti-Inflammatory Drugs In Periodontology

Effects of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in Periodontology: A Narrative Review

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Authors

AAAayushi Asthana

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Overview

Narrative review explores NSAIDs effectiveness in improving periodontal health, suggesting localized treatments are most beneficial.

Key Points

  • To review the role of NSAIDs in treating periodontitis by examining biological mechanisms and evidence from studies.
  • Conducted a structured narrative review based on a dissertation.
  • Organized evidence into categories such as mechanistic pathways and human trials.
  • Evaluated the effectiveness and safety of NSAIDs in periodontal therapy.
  • NSAIDs lower inflammatory mediators like PGE in gingival fluid.
  • They reduce alveolar bone loss in experimental models.
  • Short-term human trials show modest improvements with adjunctive use after scaling.
  • Long-term systemic use has inconsistent results and safety concerns.

Cite This Study

Aayushi Asthana (2026) studied this question.

synapsesocial.com/papers/69dc892e3afacbeac03eafdahttps://doi.org/10.5281/zenodo.19511028
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