Study reveals that elevated ApoC3 levels predict poor outcomes in aneurysmal subarachnoid hemorrhage, suggesting a potential biomarker for complications.
Key Points
This research aims to determine if ApoC3 levels in cerebrospinal fluid can predict complications in patients with aneurysmal subarachnoid hemorrhage.
Enrolled 63 patients with aneurysmal subarachnoid hemorrhage.
Performed ELISA analysis on cerebrospinal fluid samples to assess ApoC3 levels.
Evaluated predictive value using receiver operating characteristic curve analysis.
Elevated ApoC3 levels in cerebrospinal fluid were significantly associated with worse 3-month functional outcomes.
Patients with ApoC3 levels above 4,463 ng/mL had a higher incidence of delayed cerebral ischemia and hydrocephalus.
Increased ApoC3 concentrations correlated with an elevated risk of severe complications.