Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 21, 2026Letters in Organic Chemistry

Synthesis and Docking of Triazole, Pyrazole, and Schiff Base LinkedQuinazolinones for Anticancer and Antimicrobial Applications

View Full Paper
Ask AI
Bookmark
Share

Authors

MJMohammad JunaidSGSanthosh Kumar GauthamSBSrinu Bhoomandla

Discussion

Loading...

Member takes

Overview

Novel quinazolinone derivatives demonstrate anticancer and antibacterial properties, suggesting potential therapeutic applications.

Key Points

  • The aim is to synthesize novel quinazolinone derivatives and evaluate their anticancer and antimicrobial properties.
  • Synthesis of quinazolinone derivatives using various chemical reactions.
  • Evaluation of anticancer activity against multiple human cancer cell lines and normal cells.
  • Screening of antimicrobial activity against bacterial strains and Candida using well diffusion method.
  • Certain quinazolinone derivatives showed significant anticancer activity against HeLa, COLO 205, HepG2, and MCF7 cell lines.
  • Some compounds exhibited promising antibacterial effects against both Gram-positive and Gram-negative bacteria and Candida strains.

Cite This Study

Junaid et al. (2026) studied this question.

synapsesocial.com/papers/69e713b4cb99343efc98d359https://doi.org/10.2174/0115701786430284251214170953
View Full Paper
Ask AI
Bookmark
Share