ABSTRACT Aims To identify different longitudinal trajectories of hypoglycaemia problem‐solving ability in patients with diabetes mellitus (DM) and explore their predictive factors. To examine the impact of these heterogeneous trajectories on quality of life. Design This study adopted a prospective longitudinal design. Methods A total of 272 patients who completed follow‐up were longitudinally assessed for their hypoglycaemia problem‐solving abilities over 6 months. Latent class growth modelling (LCGM) was used to identify heterogeneous trajectories of hypoglycaemia problem‐solving ability. Multiple logistic regression was conducted to determine predictors, while univariate ANOVA and multiple linear regression analysis were applied to explore the effects of heterogeneous trajectories on quality of life. Results The overall level of hypoglycaemia problem‐solving ability in DM patients increased from hospitalisation to 1 month after discharge and gradually decreased from 3 to 6 months after discharge. LCGM identified three heterogeneous trajectories of hypoglycaemia problem‐solving ability. Results of multinomial logistic regression analysis showed that employment status, monthly income, frequency of blood glucose monitoring, fear of hypoglycaemia, and social support were predictors of heterogeneous trajectories of hypoglycaemia problem‐solving ability in DM patients. In addition, hypoglycaemia problem‐solving ability positively predicts quality of life. Conclusions Our findings establish a critical theoretical foundation for designing and implementing effective interventions tailored to patients' distinct trajectories in diabetes management. Implications for the Profession and/or Patient Care This study explores the trajectories and predictors of hypoglycaemia problem‐solving abilities in DM patients, providing a theoretical basis for nurses to guide patients in diabetes management. Impact Research findings indicate that nurses should regularly assess the hypoglycaemia problem‐solving abilities in DM patients, and use trajectory subgroups to identify distinct patient characteristics in hypoglycaemia problem‐solving abilities in order to implement personalised interventions. Reporting Method This study was based on the STROBE guideline. Patient or Public Contribution No patient or public engagement.
Cheng et al. (2026) studied this question.