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Evaluate the effects of standardized exercise dosage on body weight and outcomes in overweight women with knee osteoarthritis.

A case series evaluation of standardized exercise dosage using a cycle ergometer on body weight and patient-reported outcome measures among overweight female patients with knee osteoarthritis

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Case series evaluates exercise dosage effects on weight and outcomes in overweight women with knee osteoarthritis, suggesting safe improvements.

Evaluate the effects of standardized exercise dosage on body weight and outcomes in overweight women with knee osteoarthritis.
Conducted a two-phase study with n=4 participants, including a feasibility phase and an ABCB-type single-case design.
Standardized exercise dosage was defined by kilocalories per kilogram of body weight per week.
Participants performed cycle ergometer exercise along with standard physical therapy.
In Study 1, one participant safely achieved an exercise expenditure of 10 kilocalories/kg/week; adverse events occurred at 11 kilocalories/kg/week.
In Study 2, no adverse events were observed, and one participant significantly reduced body weight during Phase B2.
All participants showed improvement in Japan Knee Osteoarthritis Measure scores.

Oka et al. (2026) studied this question.

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View Full Paper

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Authors

Case series evaluates exercise dosage effects on weight and outcomes in overweight women with knee osteoarthritis, suggesting safe improvements.

Evaluate the effects of standardized exercise dosage on body weight and outcomes in overweight women with knee osteoarthritis.
Conducted a two-phase study with n=4 participants, including a feasibility phase and an ABCB-type single-case design.
Standardized exercise dosage was defined by kilocalories per kilogram of body weight per week.
Participants performed cycle ergometer exercise along with standard physical therapy.
In Study 1, one participant safely achieved an exercise expenditure of 10 kilocalories/kg/week; adverse events occurred at 11 kilocalories/kg/week.
In Study 2, no adverse events were observed, and one participant significantly reduced body weight during Phase B2.
All participants showed improvement in Japan Knee Osteoarthritis Measure scores.

Oka et al. (2026) studied this question.

View Full Paper

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