Retrospective case series evaluates meso-CISS imaging for improved CSF leak localization in SIH patients, indicating potential diagnostic benefits.
Key Points
This study aims to evaluate the effectiveness of a two-stage MRI protocol incorporating meso-CISS for localized detection of dural defects in spinal CSF leaks.
Conducted a retrospective case series of 36 patients suspected of SIH at a single center.
Used a standardized total spine MRI protocol, including HT2-MRM followed by meso-CISS for 11 SLEC-positive cases.
Assessed the imaging to determine the localization and characterization of dural defects.
Visualized dural defects in 6 out of 10 SIH patients using interpretable meso-CISS imaging, with defect sizes ranging from 0.5 to 8 mm.
Identified additional supportive features suggesting dural defects in 3 patients.
Meso-CISS provided significantly higher spatial detail compared to HT2-MRM, enhancing the accuracy of leak localization.