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May 8, 2026Microbial Genomics0 citationsOpen Access

First report of a nosocomial outbreak of ST101 Klebsiella pneumoniae carrying bla OXA-48 in Shandong, China

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WLWanxiang LiQGQizhao GaoJMJie Ma

Key Points

  • The study aims to analyze a unique nosocomial outbreak of Klebsiella pneumoniae carrying the bla OXA-48 gene to improve understanding of antibiotic resistance.
  • Documenting the outbreak of ST101 Klebsiella pneumoniae in a healthcare setting in Shandong, China.
  • Analyzing plasmid evolution related to antibiotic resistance during the outbreak.
  • Assessing current infection control strategies used in response to the outbreak.
  • Identification of a significant nosocomial outbreak featuring ST101 Klebsiella pneumoniae.
  • Demonstrated transfer of the bla OXA-48 gene among bacteria, contributing to resistance.
  • Insights provided for enhancing infection control measures in medical facilities.

Abstract

-positive CRKP. This study improves our understanding of plasmid evolution during nosocomial outbreaks and provides valuable insights to guide infection control strategies of plasmid-mediated resistance.

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Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69fd7ee0bfa21ec5bbf0732dhttps://doi.org/10.1099/mgen.0.001683
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