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March 22, 2024Cancer Research

Abstract 160: FGFR1+ cancer associated fibroblasts (CAFs) produce an extracellular matrix (ECM) that curbs infiltration of phagocytic tumor-associated macrophages (TAMs)

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Authors

NSNicolás Di SierviMRMaría V. RevueltaNZNahuel Zamponi

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Cite This Study

Siervi et al. (2024) studied this question.

synapsesocial.com/papers/68e72cdcb6db6435876a6843https://doi.org/10.1158/1538-7445.am2024-160
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abstract 3982: FGFR1+ cancer-associated fibroblasts contribute to the failure of CAR-T cell therapy in B-cell lymphoma through the secretion of TGFβ2026
  2. 2Abstract 6031: The Treg-fibroblast axis shapes the immunosuppressive tumor microenvironment in colorectal cancer2026
  3. 3Abstract 7471: Cancer-associated fibroblasts drive T cell infiltration and resistance to immunotherapy in non-small cell lung cancer with mature tertiary lymphoid structures2024 · 3 citations
  4. 4Abstract PS2-11-25: Paracrine FGFR activation by stromal signals and its association with immune infiltration in breast cancer2026
  5. 5Abstract 2710: Combination CXCR4 and PD-1 blockade increases T cell infiltration and effector function in fibrolamellar carcinoma (FLC)2024