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Synapse
February 22, 2026Age and AgeingOpen Access

Collaborative medication reviews during acute primary care admissions for older adults with polypharmacy: a randomised controlled trial

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Authors

LSLeonor Roa SantervasESEva SkovlundEKEspen Saxhaug Kristoffersen

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Overview

Randomised controlled trial evaluates collaborative medication reviews in older adults during acute admissions, suggesting no improvement in HRQoL.

Key Points

  • To assess the impact of collaborative medication reviews during acute admissions on health-related quality of life in older adults with polypharmacy.
  • Single-blind, parallel-group, randomised controlled trial design.
  • Participants aged ≥70 years on ≥6 regular medications admitted to a MIPAC unit.
  • Randomised 1:1 to receive either structured medication review or usual care.
  • Assessment involved geriatricians, general practitioners, and discussions with patients.
  • 137 participants enrolled with a mean age of 85 years; no significant difference in HRQoL scores at 16 weeks.
  • The intervention group had more medication changes during admission, but differences decreased post-discharge.
  • No significant changes observed in secondary outcomes like physical and cognitive function.

Cite This Study

Santervas et al. (2026) studied this question.

synapsesocial.com/papers/699a9dae482488d673cd3bcahttps://doi.org/10.1093/ageing/afag029
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