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March 1, 20260 citationsOpen Access

Cardiovascular Mortality Risk After Cancer Diagnosis by County-Level Characteristics in the United States 2000-2021.

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YZYenan ZhuRSRyan SukYLYueh‐Yun Lin

Key Result

Cancer survivors in rural and persistently impoverished US counties face the highest excess cardiovascular mortality, indicating need for targeted cardio-oncology care.

Key Points

  • To assess the relationship between county-level characteristics and cardiovascular mortality risk in cancer survivors.
  • Analyzed cancer survivor data from 2000-2021 across various counties in the U.S.
  • Examined cardiovascular mortality rates in relation to county-level economic and social factors.
  • Identified disparities in mortality risk based on rural and impoverished community characteristics.
  • Cancer survivors show higher cardiovascular mortality rates, particularly in rural counties.
  • Significant disparities exist where persistently impoverished counties have the highest risks.
  • Findings indicate a need for targeted cardiovascular care integration in survivorship plans.

Structured PICO

Is cardiovascular mortality risk after cancer diagnosis associated with county-level characteristics such as rurality and poverty?

P
Population
Cancer survivors in the United States between 2000-2021
O
Outcome
Cardiovascular mortalityhard clinical

Cancer survivors face excess cardiovascular mortality, particularly in rural and impoverished counties, highlighting the need for targeted cardio-oncology care in vulnerable communities.

Abstract

Cancer survivors experience substantial and sustained excess CVD mortality, with the greatest disparities in rural and persistently impoverished counties. These findings highlight the need to integrate cardiovascular surveillance into survivorship care and expand access to cardio-oncology services in socially vulnerable communities.

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Cite This Study

Zhu et al. (2026) studied this question. Cancer survivors in rural and persistently impoverished US counties face the highest excess cardiovascular mortality, indicating need for targeted cardio-oncology care.

synapsesocial.com/papers/69a3d79dec16d51705d2dd26https://doi.org/10.1002/cam4.71675
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