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March 15, 2015New England Journal of Medicine2,308 citationsOpen Access

Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events

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JRJennifer G. RobinsonMFMichel FarnierMKMichel Krempf

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Abstract

During approximately 1 year of therapy, the use of evolocumab plus standard therapy, as compared with standard therapy alone, significantly reduced LDL cholesterol levels and reduced the incidence of cardiovascular events in a prespecified but exploratory analysis. (Funded by Amgen; OSLER-1 and OSLER-2 ClinicalTrials.gov numbers, NCT01439880 and NCT01854918.).

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Robinson et al. (2015) studied this question.

synapsesocial.com/papers/69d7d5a6a2a48916bbbee039https://doi.org/10.1056/nejmoa1501031
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