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March 15, 2010New England Journal of Medicine1,035 citations

Lenient versus Strict Rate Control in Patients with Atrial Fibrillation

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IGIsabelle C. Van GelderHGHessel F. GroenveldHCHarry J.G.M. Crijns

Structured PICO

P
Population
Patients with permanent atrial fibrillation
I
Intervention
Lenient rate control
C
Comparator
Strict rate control

Lenient rate control is as effective as strict rate control and easier to achieve in patients with permanent atrial fibrillation.

Abstract

In patients with permanent atrial fibrillation, lenient rate control is as effective as strict rate control and is easier to achieve. (ClinicalTrials.gov number, NCT00392613.)

Expert Takes1 quote

“Our study suggests that lenient rate control may be adopted as the first-choice rate control strategy in patients with permanent atrial fibrillation, and this applies both for high- and low-risk patients. … If a patient comes into the office with permanent atrial fibrillation, a target resting heart rate just under 110 bpm on a 12-lead ECG is good enough.”

Isabelle C. Van Gelder, Cardiologist, University of Groningen, NetherlandsUniversity of Groningenauto_pipelineSupportiveView source
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Cite This Study

Gelder et al. (2010) studied this question.

synapsesocial.com/papers/69de8546353721b241b0c119https://doi.org/10.1056/nejmoa1001337
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