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August 26, 2020New England Journal of Medicine850 citationsOpen Access

Efficacy of Selpercatinib in RET Fusion–Positive Non–Small-Cell Lung Cancer

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ADAlexander DrilonGOGeoffrey R. OxnardDTDaniel Shao-Weng Tan

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Abstract

Selpercatinib had durable efficacy, including intracranial activity, with mainly low-grade toxic effects in patients with RET fusion-positive NSCLC who had previously received platinum-based chemotherapy and those who were previously untreated. (Funded by Loxo Oncology and others; LIBRETTO-001 ClinicalTrials.gov number, NCT03157128.).

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Drilon et al. (2020) studied this question.

synapsesocial.com/papers/69df1002d5404a0bea591be6https://doi.org/10.1056/nejmoa2005653
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