PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 16, 2026Annals of Pharmacotherapy

Erenumab and Galcanezumab for Chronic Migraine Refractory to OnabotulinumtoxinA: A Real-World Comparative Study

View Full Paper
Ask AI
Bookmark
Share

Authors

SMSara Martín-YevesADAna Colón-López de DicastilloJRJavier Riancho

Discussion

Loading...

Member takes

Overview

Real-world data show erenumab and galcanezumab effectively reduce migraine frequency in patients unresponsive to onabotulinumtoxinA, indicating their importance in treatment.

Key Points

  • The study aims to compare the effectiveness of erenumab and galcanezumab in reducing chronic migraine frequency in patients resistant to onabotulinumtoxinA.
  • Conducted a real-world comparative study
  • Included patients with chronic migraine refractory to onabotulinumtoxinA
  • Assessed migraine frequency and triptan use before and after treatment with both interventions
  • Both erenumab and galcanezumab led to sustained reductions in migraine frequency
  • High responder rates were observed for both treatments
  • Triptan use decreased significantly among patients receiving anti-CGRP monoclonal antibodies

Cite This Study

Martín-Yeves et al. (2026) studied this question.

synapsesocial.com/papers/69e07d3c2f7e8953b7cbe3echttps://doi.org/10.1177/10600280261429460
View Full Paper
Ask AI
Bookmark
Share