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Synapse
April 16, 20260 citationsOpen Access

When infant microbes guide mom's milk.

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RARosemary Abdoul AhadNJNora JosephZNZiad Al Nabhani

Key Points

  • The research aims to investigate how early infant gut microbiome states impact subsequent maternal milk composition.
  • Analyzed gut microbiome samples from infants
  • Measured nutrient and metabolite levels in maternal milk
  • Investigated timing of changes in milk composition related to microbiome state
  • Identified specific gut microbiome states that correlate with changes in milk nutrients
  • Demonstrated that these changes occur within a developmentally relevant timeframe
  • Challenged the traditional view of milk solely shaping the infant microbiome

Abstract

In the Clinical and Translational Report in Cell Host & Microbe, Deng et al. reveal that early infant gut microbiome states predict later changes in maternal milk nutrients and metabolites, uncovering developmentally timed feedback within the mother-infant dyad. This study challenges the prevailing unidirectional model of milk-driven microbial assembly.

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Cite This Study

Ahad et al. (2026) studied this question.

synapsesocial.com/papers/69e07d3c2f7e8953b7cbe4bfhttps://doi.org/10.48620/96868
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