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May 6, 2026MicroorganismsOpen Access

The Human Virome in Infectious Diseases: Insights from Chronic and Acute Infections Across Body Sites—A Narrative Review

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Authors

RFRebecca FelettiAMAntonio MoriAZAmina Zaffagnini

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Overview

Narrative review highlights chronic infections' virome changes, indicating diagnostics and prognosis potential.

Key Points

  • To summarize the composition and dynamics of the human virome in various infections.
  • Narrative review of the human virome across different body sites and infections.
  • Analysis of virome alterations in chronic infections like HIV and HPV.
  • Examination of acute infection impacts on the virome in relation to bacterial populations.
  • Chronic infections show altered virome dynamics, notably increased Torque Teno Virus levels.
  • Acute infections lead to shifts in eukaryotic viruses and bacteriophage communities.
  • Virome profiling enhances diagnostics and prognosis in infectious disease contexts.

Cite This Study

Feletti et al. (2026) studied this question.

synapsesocial.com/papers/69fa98bd04f884e66b5327e2https://doi.org/10.3390/microorganisms14050969
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