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July 31, 2025

Turning the Tide for SCLC: Real World Analysis of Atezolizumab and Platinum-based Chemotherapy in Low-Resource Settings

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Authors

UBUllas BatraSCSabeena K. ChoudharyMSMansi Sharma

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Overview

Retrospective analysis shows improved overall survival and progression-free survival in extensive-stage SCLC, indicating promise for immunotherapy in Indian patients.

Key Points

  • Atezolizumab combined with etoposide-carboplatin showed median overall survival of 11.0 months in Indian patients.
  • The study involved 38 patients, predominantly males with extensive-stage small-cell lung cancer and a high smoking history.
  • High ECOG performance status was associated with inferior survival rates, having a hazard ratio of 2.22.
  • Immunotherapy combined with standard chemotherapy demonstrated results comparable to international standards for survival outcomes.

Cite This Study

Batra et al. (2025) studied this question.

synapsesocial.com/papers/689a0c5fe6551bb0af8cf7d1https://doi.org/10.21203/rs.3.rs-6997166/v1
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