PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
September 10, 2025Drug Design Development and Therapy33 citationsOpen Access

Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment

View Full Paper
SCShuting ChenLLLing LiWDWeifeng Ding

Key Points

  • Pathogenesis of androgenetic alopecia involves factors like genetic predisposition and inflammation.
  • Finasteride and minoxidil are widely recognized as the main treatments for androgenetic alopecia.
  • Recent developments focus on drugs targeting various pathogenic mechanisms associated with androgenetic alopecia.
  • Comprehensive review aims to provide a clinical reference for effective management of androgenetic alopecia.

Abstract

Androgenetic Alopecia (AGA) is a common type of alopecia. The pathogenesis of AGA involves genetic predisposition, androgen metabolism, inflammation, fibrosis, and impaired energy metabolism. The choice of therapeutic agents for the treatment of AGA remains controversial globally, with finasteride and minoxidil being the only two widely recognized and legally approved therapeutic options. In recent years, significant progress has been made in the development of drugs targeting different pathogenic mechanisms of AGA. This article reviews the main drugs currently used for AGA treatment. By summarizing their mechanisms of action and clinical efficacy, it aims to provide a comprehensive theoretical basis and clinical reference for the treatment of AGA.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68c1d21f54b1d3bfb60f7527https://doi.org/10.2147/dddt.s542000
Ask AI
Helpful
Bookmark
Share
View Full Paper