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Background: About 95% of people with diabetes mellitus (DM) have dyslipidaemia.Dyslipidaemia is one of the major risk factors for coronary heart disease (CHD).Due to disturbances in lipoprotein levels, cardiovascular disease contributes to morbidity and mortality in DM patients.To examine the effects of lipid profiles in Type II DM patients with or without hypothyroidism.Methods: A case-control study was conducted in the Department of Medicine, Santosh Medical College and Hospital, Ghaziabad, for one year from 1st Oct. 2017 to 31st Sept. 2018 on patients attending the Medicine OPD of Santosh Medical College and Hospital.There were three groups of 25 patients compared with the single group of control, which consisted of 25 patients.Results: Mean value of triglycerides, low-density lipoprotein (LDL), total cholesterol, and lipoprotein A in Group DM, DM+Hypothyroidism, DM+subclinical hypothyroidism (DM+SCH) was significantly higher than the control group (p<0.00).Mean high-density lipoprotein (HDL) in Group DM, DM+Hypothyroidism, DM+SCH, was significantly lower than the control group (p<0.001).The mean HDL in Group DM+Hypothyroidism was significantly lower than Group DM (p<0.001).Conclusion: Dyslipidaemia in the group of overt hypothyroid diabetics is significantly higher than in the Group of subclinical hypothyroid diabetics.So, it is suggested that diabetic patients with hypothyroidism (both overt and subclinical) should undergo annual lipid status examination and corrective management as and when needed.
Sharma et al. (2024) studied this question.