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December 8, 2025BMJ Open Respiratory ResearchOpen Access

Cost-effectiveness of a self-management maintenance programme following pulmonary rehabilitation: a UK randomised controlled trial for patients with chronic obstructive pulmonary disease

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Authors

AGAnil Gumber

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Overview

Randomised controlled trial shows SPACE programme improves health utility while reducing healthcare costs in COPD patients, indicating high cost-effectiveness.

Key Points

  • To evaluate the cost-effectiveness of the Self-management Programme of Activity, Coping and Education (SPACE) following pulmonary rehabilitation in COPD patients.
  • Randomised controlled trial involving adults with COPD post pulmonary rehabilitation.
  • Participants received either SPACE or best usual care.
  • Healthcare use and costs were recorded at baseline, 6, and 12 months.
  • Health utility was measured using EQ-5D-5L with statistical analysis of differences at 6 and 12 months.
  • Cost-effectiveness was assessed using incremental cost-effectiveness ratios and sensitivity analysis.
  • 116 patients were recruited, with no significant baseline differences between groups.
  • SPACE showed a mean healthcare cost reduction of £139.72 per patient over 12 months.
  • At 12 months, the SPACE group had a higher health utility value (0.7609) compared to controls (0.6738), p=0.04.
  • The advantage in mean QALY values was 0.1178, exceeding the clinically significant threshold for COPD.
  • There was a 97% chance of SPACE being cost-effective at £20,000 per QALY.

Cite This Study

Anil Gumber (2025) studied this question.

synapsesocial.com/papers/693624d74fa91c937236d11chttps://doi.org/10.1136/bmjresp-2025-003406
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical and cost-effectiveness of SPACE for COPD delivered as a pulmonary rehabilitation maintenance programme: a randomised controlled trial2026 · 2 citations
  2. 2SPACE FOR COPD delivered as a maintenance programme on pulmonary rehabilitation discharge: protocol of a randomised controlled trial evaluating the long-term effects on exercise tolerance and mental well-being2022 · 7 citations
  3. 3Perceived Acceptability of SPACE for COPD© as a Maintenance Option Following Pulmonary Rehabilitation Discharge: A Qualitative Interview Study with Patients and Facilitators Using Framework Analysis2026
  4. 4Effectiveness of a home-based pulmonary rehabilitation maintenance programme: the Rehab2Life study protocol2024 · 3 citations
  5. 5Improving access to community-based pulmonary rehabilitation: 3R protocol for real-world settings with cost-benefit analysis2019 · 46 citations