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August 1, 2023EuroIntervention37 citationsOpen Access

Impact of mitral regurgitation aetiology on the outcomes of transcatheter aortic valve implantation

PDPhilipp M. DoldiJSJulius SteffenLSLukas Stolz

Key Result

Transcatheter aortic valve implantation significantly reduced mitral regurgitation severity, with aFMR patients showing the greatest improvement.

Structured PICO

Does transcatheter aortic valve implantation (TAVI) improve mitral regurgitation severity and symptoms across different MR aetiologies?

P
Population
Patients undergoing transcatheter aortic valve implantation (TAVI) with coexisting mitral regurgitation (atrial functional MR [aFMR], ventricular functional MR [vFMR], and primary MR [PMR]).
I
Intervention
Transcatheter aortic valve implantation (TAVI)
O
Outcome
Mitral regurgitation severity and symptomssurrogate

TAVI effectively reduces mitral regurgitation severity and symptoms, with the most significant improvement seen in patients with atrial functional mitral regurgitation.

Abstract

TAVI reduces MR severity and symptoms in patients with aFMR, vFMR and less-pronounced PMR. The presence of aFMR was associated with the greatest MR severity improvement.

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Cite This Study

Doldi et al. (2023) studied this question. Transcatheter aortic valve implantation significantly reduced mitral regurgitation severity, with aFMR patients showing the greatest improvement.

synapsesocial.com/papers/69692ad012fd9cb588971dbdhttps://doi.org/10.4244/eij-d-22-01062
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evidence of Atrial Functional Mitral Regurgitation Due to Atrial Fibrillation2011 · 471 citations
  2. 2Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients2016 · 5,090 citations
  3. 3Impact of Aortic Valve Replacement for Severe Aortic Stenosis on Organic and Functional Mitral Regurgitation2021 · 13 citations
  4. 42014 ESC/EACTS Guidelines on myocardial revascularization2014 · 4,345 citations
  5. 5Atrial Functional Mitral Regurgitation2022 · 182 citations