Coronary revascularization guided by iFR was noninferior to FFR for major adverse cardiac events, with fewer adverse signs and shorter procedural time using iFR.
Does iFR-guided coronary revascularization prevent major adverse cardiac events at 1 year as effectively as FFR-guided revascularization in patients undergoing PCI?
iFR-guided PCI is noninferior to FFR-guided PCI for 1-year major adverse cardiac events, while offering shorter procedural times and fewer adverse procedural symptoms.
Coronary revascularization guided by iFR was noninferior to revascularization guided by FFR with respect to the risk of major adverse cardiac events at 1 year. The rate of adverse procedural signs and symptoms was lower and the procedural time was shorter with iFR than with FFR. (Funded by Philips Volcano; DEFINE-FLAIR ClinicalTrials.gov number, NCT02053038 .).
Davies et al. (2017) studied this question. Coronary revascularization guided by iFR was noninferior to FFR for major adverse cardiac events, with fewer adverse signs and shorter procedural time using iFR.