Is left ventricular longitudinal systolic function, as measured by 2D speckle-tracking echocardiography, significantly altered in patients with HFpEF compared to controls?
This meta-analysis confirms that left ventricular longitudinal systolic function is significantly impaired in patients with HFpEF, highlighting the potential prognostic role of abnormal global longitudinal strain.
The present meta-analysis analysing 2284 patients with HFpEF and 2302 controls confirms that the longitudinal systolic function of the LV is significantly altered in high proportion of patients with HFpEF. Further large multicentre studies with the aim to confirm the prognostic role of abnormal GLS in HFpEF are warranted.
Morris et al. (2017) studied this question.
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