June 5, 2011New England Journal of Medicine6,376 citationsOpen Access
Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients
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Structured PICO
Does transcatheter aortic-valve replacement improve survival at 1 year in high-risk patients with severe aortic stenosis compared to surgical aortic-valve replacement?
P
Population
High-risk patients with severe aortic stenosis
I
Intervention
Transcatheter aortic-valve replacement
C
Comparator
Surgical aortic-valve replacement
O
Outcome
Survival at 1 yearhard clinical
Transcatheter and surgical aortic-valve replacement provide similar 1-year survival in high-risk patients with severe aortic stenosis.
Abstract
In high-risk patients with severe aortic stenosis, transcatheter and surgical procedures for aortic-valve replacement were associated with similar rates of survival at 1 year, although there were important differences in periprocedural risks. (Funded by Edwards Lifesciences; Clinical Trials.gov number, NCT00530894.).
Cite This Study
Smith et al. (2011) studied this question.