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March 8, 2017Gut535 citationsOpen Access

Tumour-activated neutrophils in gastric cancer foster immune suppression and disease progression through GM-CSF-PD-L1 pathway

TWTingting WangYZYongliang ZhaoLPLiu‐sheng Peng

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Abstract

Our results illuminate a novel mechanism of PD-L1 expression on tumour-activated neutrophils in GC, and also provide functional evidence for these novel GM-CSF-PD-L1 pathways to prevent, and to treat this immune tolerance feature of GC.

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Wang et al. (2017) studied this question.

synapsesocial.com/papers/69d7bf43319e71454dbed860https://doi.org/10.1136/gutjnl-2016-313075
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