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February 18, 2015New England Journal of Medicine2,871 citationsOpen Access

Driving Pressure and Survival in the Acute Respiratory Distress Syndrome

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MAMarcelo B. P. AmatoMMMaureen O. MeadeASArthur S. Slutsky

Key Points

  • This research aims to determine the relationship between driving pressure and survival in acute respiratory distress syndrome.
  • Evaluation of ventilator settings and their impact on driving pressure.
  • Analysis of survival rates in association with changes in driving pressure.
  • Data collection from various support agencies.
  • Decreases in driving pressure led to significantly increased survival rates.
  • ΔP was identified as the best indicator of risk stratification regarding survival.

Abstract

We found that ΔP was the ventilation variable that best stratified risk. Decreases in ΔP owing to changes in ventilator settings were strongly associated with increased survival. (Funded by Fundação de Amparo e Pesquisa do Estado de São Paulo and others.).

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Cite This Study

Amato et al. (2015) studied this question.

synapsesocial.com/papers/69d8d75d33ca018b39ae42a3https://doi.org/10.1056/nejmsa1410639
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