Context: Lip hyperpigmentation poses a significant concern for many patients due to its impact on aesthetics and cosmetic appearance. It remains a challenging condition to address, with limited treatment options available, each varying in efficacy. Aims: The aim of this study was to assess the effectiveness of diode laser technology in treating lip hyperpigmentation. Methods and Material: Patients with physiological lip hyperpigmentation, who had previously shown no response to other treatment modalities, were recruited for the study. Statistical Analysis Used: The Statistical Package for the Social Sciences (SPSS) software program was used. The grades of pigmentation before and after treatment were subjected to the Wilcoxon signed ranks test. A value of p < 0.05 was considered statistically significant. Results: Twelve patients participated in the study. A diode laser session was planned at baseline and then at every 2-month interval. Monthly follow-ups through serial photography were done, and the response was evaluated by a reduction in darkness and pigmentation by a special grading system at baseline and at the end of 6 months. More than 90% of the patients had a good to excellent response at the end of 6 months with a significant p -value (<0.05). Conclusions: Diode laser therapy can be considered a safe and efficacious option for managing lip hyperpigmentation, which is unresponsive to traditional treatments.
Yogesh et al. (2026) studied this question.