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May 2, 2026CureusOpen Access

Real-Time Estimation of Numerical Rating Scale (NRS) Scores Using Machine Learning-Based Facial Expression Analysis: A Proof-of-Concept Study

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Authors

KUKentaro UejimaTTTsutomu TakahashiMMMiki Matsui

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Overview

Proof-of-concept study develops a real-time pipeline for pain assessment in patients with communication limitations, indicating feasibility.

Key Points

  • This study aims to develop a real-time pipeline for estimating Numerical Rating Scale (NRS) scores based on facial expression analysis.
  • Implemented a real-time analysis pipeline using Python, integrating MediaPipe and DeepFace for facial and emotion detection.
  • Used seven emotion probability scores from 30 fps video streams as predictors for NRS estimation via regression models, including Random Forest.
  • Synthetic datasets were evaluated using leave-one-out cross-validation (LOOCV) to assess model performance.
  • In the pediatric dataset, the RF model achieved a Spearman’s rank correlation coefficient (ρ) of 0.7383 (p < 0.001) with a mean absolute error (MAE) of 1.5195, outpacing the baseline model (ρ = 0.2765).
  • In the elderly dataset, the RF model achieved ρ = 0.7566 (p < 0.001) and MAE = 1.5760.
  • Feature importance analysis found that 'Fear' was significant in both datasets, while 'Neutral' was notably important in the elderly dataset.

Cite This Study

Uejima et al. (2026) studied this question.

synapsesocial.com/papers/69f593f271405d493affebefhttps://doi.org/10.7759/cureus.107883
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Quantifying pain: An AI-driven approach to detecting pain levels via facial expressions2026
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  4. 4Detecting Feigned Pain Using an Eye‐Tracker Integrated Numerical Pain Rating Scale (<scp>NPRS</scp>)2025
  5. 5A Public Health Approach to Automated Pain Intensity Recognition in Chest Pain Patients via Facial Expression Analysis for Emergency Care Prioritization2025