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May 6, 2026The Journal of Vascular Access0 citations

Two-week postoperative duplex ultrasound as a clinical workflow tool for risk stratification of radiocephalic arteriovenous fistulas

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CRClaude J. RenaudALAllen Yan Lun LiuCHClarice Chua Kah Hwei

Key Points

  • To evaluate the efficacy of a 2-week postoperative duplex ultrasound checkpoint for risk stratification and patency prediction in radiocephalic arteriovenous fistulas.
  • Prospective single-centre study involving 57 patients
  • Assessment of vein diameter, brachial artery flow, and resistive index via duplex ultrasound 2 weeks postoperatively
  • Use of receiver operating characteristic analysis for maturation prediction
  • Kaplan-Meier and Cox regression for evaluating long-term patency
  • Brachial artery flow predicts early maturation but not long-term patency outcomes
  • Early structural parameters show no independent association with long-term primary or secondary patency
  • The 2-week duplex ultrasound checkpoint serves as a tool for early risk stratification and predicts long-term outcomes.

Abstract

BACKGROUND: Radiocephalic arteriovenous fistulas (RCAVFs) are the preferred initial haemodialysis access but are limited by high non-maturation rates, particularly in populations with smaller vessels and high diabetic burden. Preoperative duplex ultrasound (DUS) guides vessel selection but inconsistently predicts postoperative haemodynamic adaptation. We evaluated whether a standardised 2-week postoperative DUS checkpoint could function as a clinical workflow tool for early risk stratification and long-term patency prediction. METHODS: In this prospective single-centre study, 57 patients undergoing primary RCAVF creation were followed for up to 10 years. Two-week postoperative DUS assessed vein diameter (VD), brachial artery flow (BAF) and resistive index (RI). Receiver operating characteristic analysis identified thresholds predicting 6-week Kidney-Disease-Outcomes-Quality-Initiative-defined maturation. Kaplan-Meier and Cox regression analyses evaluated long-term primary (PP) and secondary patency (SP). RESULTS: = 0.01). BAF predicted early maturation but not long-term PP and SP. Early vein and flow expansion kinetics were not independently associated with long-term outcomes. CONCLUSIONS: A 2-week postoperative DUS checkpoint provides actionable early structural risk stratification after RCAVF creation. Early structural calibre reflects adaptive remodelling and independently predicts long-term PP, supporting integration of this checkpoint into routine practice.

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Cite This Study

Renaud et al. (2026) studied this question.

synapsesocial.com/papers/69fa8e3804f884e66b530792https://doi.org/10.1177/11297298261443162
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