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May 6, 2026JACC Case Reports0 citationsOpen Access

Transcatheter Folded Valve Placement Within a Patent Ductus Arteriosus for Pulmonary Hypertension

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EFEli S. FredmanHAHadeel AllamNVNidhy P. Varghese

Key Points

  • To describe a novel intervention for managing severe pulmonary arterial hypertension with a patent ductus arteriosus.
  • Case report of a 14-year-old boy with severe pulmonary arterial hypertension and bidirectional patent ductus arteriosus.
  • Transcatheter placement of a 20-mm folded Melody valve within the native patent ductus arteriosus.
  • Assessment at 1-year follow-up for shunt directionality and functional status.
  • The procedure established durable unidirectional shunting within the patent ductus arteriosus.
  • The patient improved to NYHA functional class I status after 1 year.
  • Elimination of diastolic left-to-right shunting was achieved.

Abstract

BACKGROUND: Severe pulmonary arterial hypertension (PAH) with bidirectional patent ductus arteriosus (PDA) presents a challenge, as ductal closure is contraindicated. CASE SUMMARY: A 14-year-old boy with severe PAH and bidirectional PDA experienced exercise intolerance. He underwent transcatheter placement of a 20-mm folded Melody valve within the native PDA. The procedure eliminated diastolic left-to-right shunting while preserving systolic right-to-left shunting. At 1-year follow-up, he demonstrated durable unidirectional shunting and improved to NYHA functional class I status. DISCUSSION: While surgical valved reverse Potts shunts exist in the literature, adapting a transcatheter valve to create a unidirectional shunt within the native PDA percutaneously is novel. It offers a less invasive alternative for managing suprasystemic PAH. TAKE-HOME MESSAGES: Transcatheter folded valve placement within a native PDA safely establishes a unidirectional right-to-left shunt. This intervention reduces pulmonary overcirculation while maintaining vital ventricular decompression.

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Cite This Study

Fredman et al. (2026) studied this question.

synapsesocial.com/papers/69fa98bd04f884e66b53288ahttps://doi.org/10.1016/j.jaccas.2026.108137
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