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May 6, 2026Case Reports in Dentistry0 citationsOpen Access

Incidentally Detected Odontogenic Keratocyst With Inconclusive Histopathology: A Case Report Emphasizing Clinicoradiologic Correlation

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GAGhaida ALJAMALWAWlla E. Al-HammadSASaleh N. Almohammed

Key Points

  • The aim is to emphasize the importance of clinicoradiologic correlation in diagnosing odontogenic keratocysts when histopathology is inconclusive.
  • Case report of a 61-year-old male with CBCT imaging for implant planning.
  • Lesion enucleation was performed despite inconclusive histopathology due to inflammation.
  • Follow-up recommendations included monitoring for recurrence potential.
  • Histopathology of the excised lesion was inconclusive due to inflammation.
  • CBCT revealed a pericoronal lesion with scalloped margins suggestive of an odontogenic keratocyst.
  • Emphasized need for multidisciplinary approaches in cases with obscured histological features.

Abstract

Odontogenic keratocysts (OKCs) are locally aggressive developmental odontogenic cysts that may complicate diagnosis and management. A 61-year-old male underwent CBCT for implant planning. The scan showed a pericoronal lesion with a scalloped margin and minimal expansion suggestive of OKC. The lesion was enucleated; however, histopathology was inconclusive because of inflammation and recommended clinicoradiologic correlation. Follow-up was advised because of the lesion's recurrence potential. This case highlights the need for a systematic review of the full CBCT volume and multidisciplinary correlation when classic histologic features are obscured by inflammation.

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Cite This Study

ALJAMAL et al. (2026) studied this question.

synapsesocial.com/papers/69fada7f03f892aec9b1e401https://doi.org/10.1155/crid/6449344
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1CHANGING TRENDS IN THE INCIDENCE RATE OF ODONTOGENIC KERATOCYSTS2025
  2. 2Inflammation-Modified Odontogenic Keratocyst Mimicking an Inflammatory Cyst: A Clinically Silent Case2026
  3. 3Maxillary Odontogenic Keratocyst Superimposed by Infection: Case Report2024 · 1 citations
  4. 4Multiple Odontogenic Keratocysts in a Non-Syndromic Patient: A Case Report and Review of Literature2026
  5. 5A recurrence odontogenic keratocyst formation of mandible with distinctive features: a case report2024