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May 7, 2026Endocrine0 citationsOpen Access

Comparison of vitamin D, parathyroid hormone, and body composition in obese premenopausal and postmenopausal women

BPBurcu Çaykara PeranHAHilal ADİLGÖGüler Öztürk

Key Points

  • The aim is to investigate the relationship between serum vitamin D, parathyroid hormone, and body composition in obese women.
  • Retrospective study involving 400 obese women (200 premenopausal, 200 postmenopausal)
  • Body composition assessed using bioelectrical impedance analysis
  • Biochemical parameters measured by standard laboratory methods
  • Mean serum vitamin D was lower in premenopausal women (16.91 ± 13.17 ng/mL) compared to postmenopausal women (22.59 ± 16.49 ng/mL, p < 0.05)
  • 83.75% of participants had vitamin D deficiency or insufficiency
  • In postmenopausal women, vitamin D levels negatively correlated with body weight, fat percentage, and PTH (p < 0.05)

Abstract

We aimed to investigate the associations of serum vitamin D and parathyroid hormone (PTH) with body composition parameters, including bone weight and mineral content, in obese premenopausal and postmenopausal women. In this retrospective study, 200 pre-menopausal and 200 post-menopausal obese women were evaluated. Body composition was assessed using a bioelectrical impedance analyzer (TANITA-48M), and biochemical parameters were measured by standard laboratory methods. The mean serum vitamin D level was significantly lower in pre-menopausal women compared with post-menopausal women (16.91 ± 13.17 vs. 22.59 ± 16.49 ng/mL, p 0.05). In pre-menopausal women, serum vitamin D levels were negatively correlated with PTH and mineral content. In post-menopausal women, vitamin D levels showed a negative correlation with BMI, body weight, body fat percentage, and PTH (p < 0.05). The prevalence of hypovitaminosis D was remarkably high (83.75%) among obese women. Moreover, declining vitamin D levels were associated with increased body weight and adiposity, as well as elevated PTH.

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Cite This Study

Peran et al. (2026) studied this question.

synapsesocial.com/papers/69fc2b608b49bacb8b3477bchttps://doi.org/10.1007/s12020-026-04652-1
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