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May 8, 2026Veterinary Quarterly1 citationsOpen Access

Prognostic interaction between clinical stage and left atrial remodeling in dogs with myxomatous mitral valve disease

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SPSin-Wook ParkKKKeon KimKYKyung-Ho You

Key Points

  • The aim is to evaluate how left atrial remodeling interacts with clinical stage to influence prognosis in dogs with myxomatous mitral valve disease.
  • Evaluated dogs diagnosed with myxomatous mitral valve disease
  • Measured left atrial (LA) size to assess remodeling
  • Analyzed survival outcomes based on clinical stage and LA size
  • Severe LA enlargement in preclinical disease worsens prognosis, similar to CHF with mild-to-moderate LA enlargement
  • Prognosis cannot be determined by clinical stage alone; LA remodeling impacts outcomes significantly

Abstract

= 0.032). Severe LA enlargement in dogs with preclinical disease contributes to a poor prognosis comparable to that of CHF with mild-to-moderate enlargement, indicating that stage alone may be insufficient for determining prognosis and that LA remodeling should also be considered.

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Cite This Study

Park et al. (2026) studied this question.

synapsesocial.com/papers/69fd7e42bfa21ec5bbf067c1https://doi.org/10.1080/01652176.2026.2668790
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