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March 8, 2013European Journal of Cardio-Thoracic Surgery96 citationsOpen Access

Effect of annulus dimension and annuloplasty on bicuspid aortic valve repair†

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ENEmiliano NavarraGKGébrine El KhouryDGDavid Glineur

Key Result

Valve sparing reimplantation offered greater reduction of the ventriculo-aortic junction compared with subcommissural annuloplasty (21 vs 24 mm, P<0.01), positively influencing repair durability.

Study Design

Type

Cohort (n=118)

Structured PICO

Does valve sparing reimplantation improve annular reduction and repair durability compared to subcommissural annuloplasty in patients undergoing bicuspid aortic valve repair?

P
Population
118 patients who underwent bicuspid aortic valve repair (53 with subcommissural annuloplasty and 65 with reimplantation) having intraoperative pre- and post-repair transoesophageal echocardiography images.
I
Intervention
Valve sparing reimplantation (VSR)
C
Comparator
Subcommissural annuloplasty
O
Outcome
Degree of annular reduction (ventriculo-aortic junction [VAJ] diameter) and repair durability (recurrent aortic regurgitation > 1+)surrogate

Valve sparing reimplantation offers greater reduction of the ventriculo-aortic junction compared to subcommissural annuloplasty, which positively influences repair durability, particularly in patients with a large VAJ.

Main Result

Absolute Event Rate: 21% vs 24%

p-value: p=<0.01

Abstract

OBJECTIVES: We have recently shown that valve sparing reimplantation (VSR) improves the durability of bicuspid aortic valve repair in comparison with subcommissural annuloplasty. The aim of this study was to assess the degree of annular reduction provided by these techniques and to correlate these findings with repair durability. METHODS: From 1995 to 2010, 161 patients underwent bicuspid valve repair. We included only patients with subcommissural annuloplasty or reimplantation having intraoperative pre- and post-repair transoesophageal echocardiography images. Pre- and post-repair ventriculo-aortic junction (VAJ) diameters were measured on long axis views. Inclusion criteria were met by 53 patients with subcommissual annuloplasty and 65 with reimplantation. Median follow-up was 53 months in the subcommissual annuloplasty group and 42 months in the reimplantation group. Follow-up completeness was 100% in subcommissural annuloplasty and 94% in reimplantation. RESULTS: There was no operative or late mortality. Mean preoperative VAJ was similar in both groups (reimplantation: 28 ± 3 mm vs subcommissural annuloplasty: 28 ± 3, P = 0.16). Preoperative VAJ was larger in patients 1+. In the subcommissural annuloplasty group, VAJ≥ 30 mm preoperatively and ≥ 25 mm postoperatively were associated with decreased 6 years freedom from recurrent AR>1+ (1+ (P = 0.93). CONCLUSIONS: In bicuspid aortic valve repair, the circumferential annuloplasty of VSR offers greater reduction of VAJ compared with the non-circumferential annuloplasty provided by the subcommissural annuloplasty. The degree and extent of VAJ reduction in reimplantation seem to be factors among others that positively influence repair durability particularly in patients with a large VAJ (≥ 30 mm).

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Cite This Study

Navarra et al. (2013) conducted a cohort in Bicuspid aortic valve disease (n=118). Valve sparing reimplantation vs. Subcommissural annuloplasty was evaluated on Mean postoperative ventriculo-aortic junction (VAJ) diameter (mm) (p=<0.01). Valve sparing reimplantation offered greater reduction of the ventriculo-aortic junction compared with subcommissural annuloplasty (21 vs 24 mm, P<0.01), positively influencing repair durability.

synapsesocial.com/papers/6a09082aea37c9c7dbe46b7chttps://doi.org/10.1093/ejcts/ezt045
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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