PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
May 20, 2026American Journal of Respiratory and Critical Care Medicine

B35-49 A Case of Granulomatosis With Polyangiitis Complicated by Left Mainstem Bronchus Obstruction

View Full Paper
Ask AI
Bookmark
Share

Authors

ABA BaidwanMLM LobjanidzeJGJ Gooden

Discussion

Loading...

Member takes

Overview

Case report describes granulomatosis with polyangiitis causing bronchial obstruction, suggesting early intervention improves outcomes.

Key Points

  • This case report highlights the rare complication of bronchial obstruction in granulomatosis with polyangiitis (GPA) and its treatment.
  • Reported on a 54-year-old Japanese female presenting with pulmonary symptoms and airway obstruction.
  • Performed bronchoscopy, cytoplasmic anti-neutrophil cytoplasmic antibodies testing, and CT-guided lung biopsy.
  • Administered high-dose steroids, rituximab, and monitored clinical improvement.
  • Initial treatment with steroids led to symptom improvement but resulted in subsequent relapse with hemoptysis and epistaxis.
  • The patient received pulse steroids and rituximab for vasculitis flare and showed clinical recovery.
  • Histologic findings confirmed necrotizing vasculitis, aiding diagnosis and treatment decision.

Cite This Study

Baidwan et al. (2026) studied this question.

synapsesocial.com/papers/6a0d4ec0f03e14405aa99fd5https://doi.org/10.1093/ajrccm/aamag162.776
View Full Paper
Ask AI
Bookmark
Share