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August 25, 2025Molecular Carcinogenesis0 citations

RETRACTION: SENP2 Suppresses Epithelial‐Mesenchymal Transition of Bladder Cancer Cells Through deSUMOylation of TGF‐βRI

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Key Points

  • The retraction indicates serious concerns over image duplication affecting the reliability of results.
  • Image duplications were confirmed between various figures, leading to compromised conclusions about senp2's role.
  • A third-party complaint initiated the investigation, resulting in the retraction by Wiley Periodicals LLC.
  • The authors consented to the retraction but contested the allegations of duplication in their research.

Abstract

RETRACTION: M. Tan, D. Zhang, E. Zhang, D. Xu, Z. Liu, J. Qiu, Y. Fan, and B. Shen, “SENP2 Suppresses Epithelial‐Mesenchymal Transition of Bladder Cancer Cells Through deSUMOylation of TGF‐βRI,” Molecular Carcinogenesis 56, no. 10 (2017): 2332‐2341. https://doi.org/10.1002/mc.22687 . The above article, published online on 02 June 2017, in Wiley Online Library ( wileyonlinelibrary.com ), has been retracted by Wiley Periodicals LLC. A third party reported to the journal that image elements in Figure 2E of this article had been duplicated and manipulated from a previously published article by a different group of authors and reporting different experimental conditions (Mani et al. 2007 https://doi.org/10.1073/pnas.0703900104 ). Further investigation by the publisher confirmed this duplication and also detected additional duplications between the T24‐Vector panel of Figure 5A and the first panel of Figure 5B, as well as duplication and rotation of image elements in the T24‐SENP2 panel of Figure 5A and the third panel of Figure 5B. The authors responded to an inquiry by the publisher and stated that there were no issues of duplication between different articles and that the duplications in Figure 5 may have been caused by errors during image preparation. However, the authors were unable to provide original, unmodified data or images for the experiments reported. The retraction has been agreed to because of the duplication of images from another article, as well as duplication and rotation of images and image elements within the same article, which fundamentally compromises the reported conclusions. The authors have stated their consent to the retraction. The authors disagree with the retraction as they have stated they do not agree that image elements were duplicated in Figure 2E.

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Cite This Study

A 2025 study studied this question.

synapsesocial.com/papers/68af55d1ad7bf08b1eadc5e1https://doi.org/10.1002/mc.70038
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