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September 17, 2025Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

Focused Ultrasound sonications in a tumor-bearing head phantom within a high field MRI scanner

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Authors

AAAnastasia AntoniouNENikolas EvripidouLGLeonidas Georgiou

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Overview

This analysis demonstrates focused ultrasound's potential for tumor ablation in phantoms, suggesting implications for MRI-guided techniques.

Key Points

  • Hyperintense lesions were seen in the tumor simulator, achieving complete tumor coverage regardless of the skull's presence.
  • Robotic sonications were conducted in a 3T MRI scanner, with tumor ablation monitored through thermometry and high-resolution imaging.
  • A biocompatible implant was used to temporarily replace a skull segment, enabling focused ultrasound ablation of tumors.
  • The study provides initial insights into using phantoms for evaluating MRI-guided focused ultrasound protocols in clinical settings.

Cite This Study

Antoniou et al. (2025) studied this question.

synapsesocial.com/papers/68d4597031b076d99fa5c722https://doi.org/10.58530/2025/2187
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of Three-dimensional-printed Skull Inserts of Different Thickness on Magnetic Resonance-guided Focused Ultrasound Heating in a Head Phantom2025
  2. 2Phantoms for magnetic resonance imaging-guided focused ultrasound and associated robotic systems research2026
  3. 3Utilizing an Agar/Silica Phantom for Magnetic Resonance Imaging-guided Focused Ultrasound Evaluation: Lesion Formation, Magnetic Resonance Imaging Manifestation, and Comparison with Porcine Tissue2025
  4. 4Histology-validated quantitative MRI assessment of non-thermal focused ultrasound ablation2026
  5. 5Agar-based Phantom for Evaluating Targeting of High-intensity Focused Ultrasound Systems for Breast Ablation2024 · 2 citations